林研究室所属
米光 新（京都大学博士（医学））
論題：Troglitazone Induces GLUT4 Translocation in L6 Myotubes.（L6筋管細胞を用いたトログリタゾンのGLUT４トランスロケーション促進作用に関する研究）
Yonemitsu S, Nishimura H, Shintani M, Inoue R, Yamamoto Y, Masuzaki H, Ogawa Y, Hosoda K, Inoue G, Hayashi T, Nakao K. Troglitazone induces GLUT4 translocation in L6 myotubes. Diabetes. 50:1093-1101, 2001.
豊田 太郎（京都大学博士（農学））
論題：Studies on AMP independent activation of the 5'AMP-activated protein kinase involved in muscle contraction-induced glucose transport.（筋収縮が引き起こす糖輸送促進に関わるAMPキナーゼのAMP非依存的な活性化に関する研究）
Toyoda T, Hayashi T*, Miyamoto L, Yonemitsu S, Nakano M, Tanaka S, Ebihara K, Masuzaki H, Hosoda K, Inoue G, Otaka A, Sato K, Fushiki T, Nakao K. Possible involvement of the alpha1 isoform of 5'AMP-activated protein kinase in oxidative stress-stimulated glucose transport in skeletal muscle. Am J Physiol Endocrinol Metab. 287:E166-173, 2004.
Toyoda T, Tanaka S, Ebihara K, Masuzaki H, Hosoda K, Sato K, Fushiki T, Nakao K, Hayashi T*. Low-intensity contraction activates the alpha1-isoform of 5'-AMP-activated protein kinase in rat skeletal muscle. Am J Physiol Endocrinol Metab. 290:E583-590, 2006.
宮本 理人（京都大学博士（医学））
論題：Effect of Acute Activation of 5'-AMP-Activated Protein Kinase on Glycogen Regulation in Isolated Rat Skeletal Muscle.（ラット骨格筋における急性のAMPK活性化がグリコーゲン制御におよぼす効果）
Miyamoto L, Toyoda T, Hayashi T*, Yonemitsu S, Nakano M, Tanaka S, Ebihara K, Masuzaki H, Hosoda K, Ogawa Y, Inoue G, Fushiki T, Nakao K. Effect of acute activation of 5'-AMP-activated protein kinase on glycogen regulation in isolated rat skeletal muscle. J Appl Physiol. 102:1007-1013, 2007.
中野 雅子（京都大学博士（医学））
論題：α2 Isoform-specific activation of 5' adenosine monophosphate-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-β-D-ribonucleoside at a physiological level activates glucose transport and increases glucose transporter 4 in mouse skeletal muscle.（骨格筋5'AMPキナーゼα2アイソフォームの生理レベル活性化によって生じる糖輸送活性化と糖輸送担体増加）
Nakano M, Hamada T, Hayashi T*, Yonemitsu S, Miyamoto L, Toyoda T, Tanaka S, Masuzaki H, Ebihara K, Ogawa Y, Hosoda K, Inoue G, Yoshimasa Y, Otaka A, Fushiki T, Nakao K. Alpha2 isoform-specific activation of 5'adenosine monophosphate-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-d-ribonucleoside at a physiological level activates glucose transport and increases glucose transporter 4 in mouse skeletal muscle. Metabolism. 55:300-308, 2006.
田中 早津紀（京都大学博士（医学））
論題：High-fat diet impairs the effects of a single bout of endurance exercise on glucose transport and insulin sensitivity in rat skeletal muscle.（高脂肪食による運動誘発性骨格筋糖代謝活性化の発現阻害に関する研究）
Tanaka S, Hayashi T*, Toyoda T, Hamada T, Shimizu Y, Hirata M, Ebihara K, Masuzaki H, Hosoda K, Fushiki T, Nakao K. High-fat diet impairs the effects of a single bout of endurance exercise on glucose transport and insulin sensitivity in rat skeletal muscle. Metabolism. 56:1719-1728, 2007.
増田 慎也（京都大学博士（人間・環境学））（田口貞善研究室→林研究室）
論題：Adaptation of cytoskeletal and sarcolemmal proteins for functional requirements - new information for the development of fatigue resistance in skeletal muscle -（機能的要求に対する細胞骨格および筋細胞膜タンパク質の適応 - 骨格筋の耐疲労性の発達に関する新たな知見 -）
Masuda S, Hayashi T*, Egawa T, Taguchi S. Evidence for differential regulation of lactate metabolic properties in aged and unloaded rat skeletal muscle. Exp Gerontol. 44:280-288, 2009.
Masuda S, Hayashi T*, Hashimoto T, Taguchi S. Correlation of dystrophin-glycoprotein complex and focal adhesion complex with myosin heavy chain isoforms in rat skeletal muscle. Acta Physiol (Oxf). 195:483-494, 2009.
増田慎也君は本ウェブサイトの作成者・管理者です
岩中 伸壮（京都大学博士（人間・環境学））
論題：Leucine modulates contraction- and insulin-stimulated glucose transport and upstream signaling events in skeletal muscle（筋収縮及びインスリンによる骨格筋糖輸送活性化とそのシグナル伝達におけるロイシンの調節作用に関する研究）
Iwanaka N, Egawa T, Satoubu N, Karaike K, Ma X, Masuda S, Hayashi T*. Leucine modulates contraction- and insulin-stimulated glucose transport and upstream signaling events in rat skeletal muscle. J Appl Physiol. 108:274-282, 2010.
馬 嘯（京都大学博士（人間・環境学））
論題：Active Ingredient of Chinese Medicinal Plant Rapidly Activates 5'AMP－Activated Protein Kinase in Skeletal Muscle（中国由来薬用植物成分による骨格筋5'AMP－活性化プロテインキナーゼの急性活性化作用に関する研究）
Ma X, Iwanaka N, Masuda S, Karaike K, Egawa T, Hamada T, Toyoda T, Miyamoto L, Nakao K, Hayashi T*. Morus alba leaf extract stimulates 5'-AMP-activated protein kinase in isolated rat skeletal muscle. J Ethnopharmacol. 122:54-59, 2009.
Ma X, Egawa T, Kimura H, Karaike K, Masuda S, Iwanaka N, Hayashi T*. Berberine-induced activation of 5'AMP-activated protein kinase and glucose transport in rat skeletal muscles. Metabolism. 59:1619-27, 2010.
2009年度 中国留日同学会賞（中国留日同学会）受賞
2009年度 国家優秀自費留学生奨学金（中国教育部）受賞
江川 達郎（京都大学博士（人間・環境学））
論題：MULTIPLE EFFECTS OF CAFFEINE ON SKELETAL MUSCLE GLUCOSE TRANSPORT AND UPSTREAM SIGNALING EVENTS -ACTIVATION OF 5'AMP-ACTIVATED PROTEIN KINASE AND SUPPRESSION OF INSULIN SIGNAL TRANSDUCTION-（カフェインによる骨格筋糖輸送およびその関連シグナルに及ぼす相互作用に関する研究－AMPキナーゼ活性化とインスリンシグナル伝達抑制－）
Egawa T, Tsuda S, Ma X, Hamada T, Hayashi T*. Caffeine modulates phosphorylation of insulin receptor substrate (IRS)-1 and impairs insulin signal transduction in rat skeletal muscle. J Appl Physiol. 111: 1629-36, 2011.
Egawa T, Hamada H, Ma X, Karaike K, Kameda N, Masuda S, Iwanaka N, Hayashi T*. Caffeine activates preferentially α1-isoform of 5'AMP-activated protein kinase in rat skeletal muscle. Acta Physiol (Oxf). 201: 227-38, 2011.
Egawa T, Hamada T, Kameda N, Karaike K, Ma X, Masuda S, Iwanaka N, Hayashi T*. Caffeine acutely activates 5' AMP-activated protein kinase and increases insulin-independent glucose transport in rat skeletal muscles. Metabolism. 58:1609-1617, 2009.
平成23年度（第24回）中冨健康科学振興財団研究助成「骨格筋量減少因子としてのAMPキナーゼの役割の解明」
平成24年度日本学術振興会特別研究員PD（豊橋創造大学後藤勝正研究室）
城尾 恵里奈（京都大学博士（人間・環境学））（津田謹輔研究室→林研究室）
論題：The effects of nutrition intake on intestinal mucosal repair and metabolic regulation through gut hormones（栄養摂取の消化管ホルモンを介した腸管粘膜修復ならびに代謝調節に及ぼす影響）
Joo E, Yamane S, Hamasaki A, Harada N, Matsunaga T, Muraoka A, Suzuki K, Nasteska D, Fukushima T, Hayashi T, Tsuji H, Shide K, Tsuda K, Inagaki N. Enteral supplement enriched with glutamine, fiber, and oligosaccharide attenuates experimental colitis in mice. Nutrition. 29:549-55, 2013.
大島 里詠子（京都大学博士（人間・環境学））
論題：Evidence for acute activation of 5'-AMP-activated protein kinase by metformin and salicylate in rat skeletal muscles （ラット骨格筋におけるメトホルミン及びサリチル酸によるAMPキナーゼの急性的活性化に関する検討）
Oshima R, Yamada M, Kurogi E, Ogino Y, Serizawa Y, Tsuda S, Ma X, Egawa T, Hayashi T*. Evidence for organic cation transporter-mediated metformin transport and 5'-adenosine monophosphate-activated protein kinase activation in rat skeletal muscles. Metabolism. 64(2):296-304, 2015.
Serizawa Y, Oshima R*, Yoshida M, Sakon I, Kitani K, Goto A, Tsuda S, Hayashi T. Salicylate acutely stimulates 5'-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscles. Biochem Biophys Res Commun. 453(1):81-5, 2014.
後藤 亜由美（京都大学博士（人間・環境学））
論題：Effects of acute heat stress on glucose metabolism and 5' adenosine monophosphate-activated protein kinase in skeletal muscle（急性的な熱刺激が骨格筋糖代謝とAMPキナーゼに及ぼす影響）
Goto A, Egawa T, Sakon I, Oshima R, Ito K, Serizawa Y, Sekine K, Tsuda S, Goto K, Hayashi T*. Heat stress acutely activates insulin-independent glucose transport and 5'-AMP-activated protein kinase prior to an increase in HSP72 protein in rat skeletal muscle. Physiol Rep. 3 (11): e12601, 2015.
平成28年度石本記念デサントスポーツ科学振興財団研究助成「短時間の温熱刺激が骨格筋糖輸送活性促進に及ぼすメカニズムの解明」
本田 寛人（京都大学博士（人間・環境学））
論題：Effects of stair climbing-descending exercise for a short time after a meal on postprandial hyperglycemia and glycemic control in people with type 2 diabetes
（食後に実施する短時間の階段昇降運動が2型糖尿病患者の食後高血糖および血糖コントロールに及ぼす影響）
Honda H, Takaishi T, Hayashi T*. Acute and chronic effects of exercise on glucose metabolism. Nihon Rinsho. 74(Suppl 1): 495-500, 2016.
Honda H, Igaki M, Hatanaka Y, Komatsu M, Tanaka S, Miki T, Suzuki T, Takaishi T, Hayashi T*. Stair climbing/descending exercise for a short time decreases blood glucose levels after a meal in people with type 2 diabetes. BMJ Open Diab Res Care. 4: e000232, 2016.
Honda H*, Igaki M, Hatanaka Y, Komatsu M, Tanaka S, Miki T, Matsuki Y, Takaishi T, Hayashi T. Repeated 3-minute stair climbing-descending exercise after a meal over 2 weeks increases serum 1,5-anhydroglucitol levels in people with type 2 diabetes. J Phys Ther Sci. 29(1):75-8, 2017.
第3回（2019年度）日本糖尿病学会 医療スタッフ優秀演題賞
横川 拓海（京都大学博士（人間・環境学））
論題：Exercise training increases expression of mitochondrial translation factors and CISD family
（運動トレーニングはミトコンドリア翻訳因子およびCISDファミリーの発現を増加させる）
Yokokawa T, Kido K, Suga T, Isaka T, Hayashi T, Fujita S*. Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle. Physiol Rep. 6 (20), e13893, 2018.
Yokokawa T, Kido K, Suga T, Sase K, Isaka T, Hayashi T, Fujita S*. Exercise training increases CISD family protein expression in murine skeletal muscle and white adipose tissue. Biochem Biophys Res Commun. 506, 571-577, 2018.
津田 諭志（京都大学博士（人間・環境学））
論題：Metabolic effects of coffee components on rat skeletal muscle in the resting and contracting states ―Evidence for 5'AMP-activated protein kinase activation, glucose metabolism enhancement, and ergogenic effect―
（コーヒー成分が安静時および収縮時のラット骨格筋に及ぼす代謝的効果 ―AMPキナーゼ活性化、糖代謝促進および運動機能増進作用の検証―）
Tsuda S, Egawa T*, Ma X, Oshima R, Kurogi E, Hayashi T. Coffee polyphenol caffeic acid but not chlorogenic acid increases 5'AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle. J Nutr Biochem. 23: 1403 - 1409, 2012.
Tsuda S*, Egawa T, Kitani K, Oshima R, Ma X, Hayashi T. Caffeine and contraction synergistically stimulate 5'-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle. Physiol Rep. 3 (10):e12592, 2015.
Tsuda S, Hayashi T, Egawa T*. The effects of caffeine on metabolomic responses to muscle contraction in rat skeletal muscle. Nutrients. 11(8), 1819, 2019.
辻田 那月（京都大学博士（人間・環境学））（森谷敏夫研究室→林研究室）
論題：The characteristics of young adults with subclinical depression and the beneficial effect of tryptophan, vitamin B6, and nicotinamide-containing supplement loading between meals on their depressive mood
（抑うつ傾向の若年成人の特徴とトリプトファン・ビタミンB6・ニコチンアミド含有サプリメントの食間摂取による抑うつ気分の改善効果）
Tsujita N, Akamatsu Y, Nishida MM, Hayashi T, Moritani T*. Effect of tryptophan, vitamin B6, and nicotinamide-containing supplement loading between meals on mood and autonomic nervous system activity in young adults with subclinical depression: a randomized, double-blind, and placebo-controlled study. J Nutr Sci Vitaminol. 65: 507-514, 2019.
Tsujita N, Akamatsu Y, Nishida MM, Hayashi T, Moritani T*. Physical activity, nutritional status, and autonomic nervous system activity in healthy young adults with higher levels of depressive symptoms and matched controls without depressive symptoms: a cross-sectional study. Nutrients. 12(3), 690, 2020.
認知・行動科学講座 森谷敏夫研究室所属
浜田 拓（京都大学博士（人間・環境学））
論題：NEUROMUSCULAR AND METABOLIC RESPONSES TO ELECTRICAL STIMULATION OF HUMAN SKELETAL MUSCLE.（ヒト骨格筋電気刺激における神経・筋、代謝応答）
Hamada T, Sasaki H, Hayashi T*, Moritani T, Nakao K. Enhancement of whole body glucose uptake during and after low-frequency electrical stimulation of human skeletal muscle. J Appl Physiol. 94:2107-2112, 2003.
Hamada T, Hayashi T, Kimura T, Nakao K, Moritani T. Electrical stimulation of human lower extremities enhances energy consumption, carbohydrate oxidation and whole body glucose uptake. J Appl Physiol. 96:911-916, 2004.
分子・生命環境論講座 山本行男研究室所属
神山 直樹（京都大学博士（人間・環境学））
論題：Synthesis of Nucleoside Derivatives Directed toward Clarification of Glucose Metabolism Activation.（糖代謝活性化機構解明を目指したヌクレオシド誘導体の合成）
Kohyama N, Hayashi T, Yamamoto Y. Synthesis of a methylene analog of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide monophosphate (ZMP). Biosci Biotechnol Biochem. 69:836-838, 2005.
* corresponding author